CapCell: Innovative forensic trace investigation via microfluidics and single-cell genomics

A Horizon Europe Research and Innovation Action funded under HORIZON-CL3-2024-FCT-01.

Overview

CapCell is an EU-funded research project that aims to revolutionise forensic DNA analysis to deliver more justice for victims of sexual violence. By combining microfluidics and single-cell genomics, the project develops a new toolkit to isolate and interpret individual DNA profiles from complex biological mixtures. Forensic practitioners across Europe will be able to use these tools for improved identification of perpetrators.

Key facts

Project

CapCell introduces the first modular forensic toolkit capable of capturing, isolating, sequencing, and interpreting single cells from mixed DNA samples. This innovation will help extract reliable, single-source DNA profiles even from the most complex traces.

Network

Led by Maastricht University, CapCell brings together 13 partners from 8 European countries, including universities, forensic institutes, SMEs, and police forces, to jointly develop, validate, and implement this groundbreaking technology in real forensic environments.